Spindle is named after Friedrich Ernst Krukenberg (1871-1946), a
German gynaecologist and pathologist, specialising in Ophthalmology.
He was a fellow of the German ophthalmologist Karl Theodor Paul
Polykarpus Axenfeld (1867-1930). Krukenberg's Spindle is also referred
to as Axenfeld-Krukenberg Spindle.
is a spindle-shaped, vertical deposit of chocolate-brown coloured
pigment in the cornea of the eye, created by flakes of pigment rubbed
off the back of the iris. The reasons for this aren't exactly known...
some researchers believe it to be congenital, others believe that
it is the shape of the iris itself which causes this to happen.
There is research in progress to try to find the gene(s) responsible
for this condition.
courtesy of: http://www.opt.indiana.edu/Riley/
Spindle is an early indicator of Pigment
Dispersion Syndrome, which can lead to Pigmentary Glaucoma.
Usually, it is detected during a routine eye examination; there
are usually no symptoms that KS or PDS are present until an examination
to some sites relating to Krukenberg's Spindle and Pigment Dispersion
Syndrome are available on the Links page
of this site.
Ernst Krukenberg (1871-1946)
Picture courtesy of http://www.dsog.dk/files/krugen.htm